AEG 3482
AEG3482 is a potent antiapoptotic compound that inhibits Jun kinase (JNK) activity through induced expression of heat shock protein 70 (HSP70) . AEG3482 directly binds HSP90, thereby facilitating HSF1-dependent expression of HSP70 and HSP25.
Product Specifications
CAS Number
63735-71-7
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 250 mg/mL (891.81 mM; Ultrasonic)
Smiles
NS (=O) (=O) c1nn2cc (nc2s1) -c1ccccc1
Molecular Formula
C10H8N4O2S2
Molecular Weight
280.33
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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