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Glyoxalase I inhibitor 3

Selected Variant

HY-146655-01

Size: 5 mg

Glyoxalase I inhibitor 3 (compound 22g) is a potent glyoxalase I (GLO1) inhibitor with an IC50 of 0.011 µM. Glyoxalase I inhibitor 3 has the potential for the research of depression and anxiety[1].

Product Specifications

CAS Number

1415388-25-8

UNSPSC

12352005

Target

Glyoxalase (GLO)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/glyoxalase-i-inhibitor-3.html

Purity

98.06

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1C=C(C2=CC=CC=C2)C=C(N1O)C3=CN=C4C(C=CN4CCCOC)=C3

Molecular Formula

C22H21N3O3

Molecular Weight

375.42

References & Citations

[1]Jin T, Zhao L, et al. Recent advances in the discovery and development of glyoxalase I inhibitors. Bioorg Med Chem. 2020 Feb 15;28 (4) :115243.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Price

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