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M4K2281

M4K2281 is a potent and selective ALK2 inhibitor with a biochemical IC50 of 2 nM, demonstrating efficacy in cellular assays. Its moderate-to-high brain-to-plasma ratio supports its utility in researching ALK2-related pathologies, including fibrodysplasia ossificans progressiva (FOP), in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

3034840-19-9

Smiles

N1=CC (C2=CC (OC) =C (OC) C (OC) =C2) =C3C (=C1) C4=CC=C (C=C4OCC3) N5CCN (C) CC5

Molecular Formula

C27H31N3O4

Molecular Weight

461.55

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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