VEGFR-2/AKT-IN-2
VEGFR-2/AKT-IN-2 (Compound 5) is a dual inhibitor targeting VEGFR-2 and AKT signaling, demonstrating potent anti-proliferative activity in human liver cancer cell models. It induces apoptosis via caspase-3 activation and Bcl-2/BAX modulation and arrests the cell cycle in S-phase, supporting its investigation in oncology research for hepatocellular carcinoma.
Product Specifications
Field of Research
Cardiovascular Research, Cardiovascular Research; Cell Biology, Cell Biology, Protein Biochemistry, Signal Transduction
Molecular Formula
C25H16FN5S
Molecular Weight
437.49
Storage Conditions
-20°C
Notes
For research use only.
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