HDAC-IN-76

HDAC-IN-76 is a potent HDAC inhibitor with robust antimalarial activity against both drug-sensitive (Pf3D7, IC50 30 nM) and drug-resistant (PfDd2, IC50 98 nM) Plasmodium asexual blood stages. It selectively targets PfHDAC1 and is a valuable tool for investigating epigenetic mechanisms in malaria parasite biology and drug discovery research.