MPGES1-IN-4
MPGES1-IN-4 (compound 32) is a multi-substituted pyrimidine that acts as a submicromolar inhibitor of microsomal prostaglandin E synthase-1 (mPGES-1), effectively reducing PGE2 production. It demonstrates anti-inflammatory activity in both cellular assays and in vivo models of acute inflammation, making it a useful research tool for studying prostaglandin biology and inflammation pathways.
Product Specifications
CAS Number
2253745-78-5
Field of Research
Immunology & Inflammation
Smiles
FC=1C (F) =C (C=CC1OCC=2C=CC=CC2) C=3N=C (N=C (C=4C=CC=CC4) C3CCCC) N
Molecular Formula
C27H25F2N3O
Molecular Weight
445.50
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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