TH-Z816
Product Specifications
CAS Number
2847881-42-7
Target
Ras, Kras
Related Pathways
MAPK, GPCR/G Protein
Bioactivity
TH-Z816 acts as a reversible inhibitor targeting the KRAS (G12D) mutation, exhibiting an IC50 of 14 μM. This compound is utilized in cancer research [1].
Smiles
C[C@H]1N(C2=C3C(CN(CC3)C=4C5=C(C=CC4)C=CC=C5C)=NC(OC[C@H]6N(C)CCC6)=N2)CCNC1
Molecular Formula
C29H38N6O
Molecular Weight
486.65
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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