Tubulin polymerization-IN-69

Tubulin polymerization-IN-69 (6c) is a potent small molecule inhibitor of microtubule assembly, demonstrating an IC50 of 6.53 μM and 78.3% inhibition in vitro. It triggers rapid G2/M phase arrest and apoptosis in MCF-7 cells, making it a useful chemical probe for studying cell cycle dynamics and anticancer mechanisms in cancer research.