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NT-0249

NT-0249 is a potent, orally bioavailable NLRP3 inflammasome inhibitor. It demonstrates anti-inflammatory effects in research models, reversing obesity, systemic inflammation, and astrocyte hyperplasia induced by a high-fat diet. This small molecule is a valuable tool for studying NLRP3-driven pathologies in metabolic and neuroinflammatory research.

Product Specifications

CAS Number

2763617-39-4

Product Name Alternative

NLRP3, NT0249

Field of Research

Immunology & Inflammation, Signal Transduction

Purity

98.11% (May vary between batches)

Smiles

[N-] (C (NS (N (C[C@@H]1CCCO1) C2=CN (C) N=C2) (=O) =O) =O) C3=C4C (=CC5=C3CCC5) CCC4.[Na+]

Molecular Formula

C22H28N5NaO4S

Molecular Weight

481.54

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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