HBG1/HBG2 Polyclonal Antibody
This is a HBG1/HBG2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1) . The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.
Synonyms
A gamma globin, G gamma globin, Gamma 1 globin, Gamma 2 globin, Gamma A hemoglobin, Gamma globin, Hb F Agamma, Hb F Ggamma, hbfagamma, hbfggamma, HBG 1, HBG 2, HBG1, HBG2, HBGA, HBGR, Hemoglobin gamma 1 chain , Hemoglobin gamma 2 chain , Hemoglobin gamma A, Hemoglobin gamma
Swiss Prot
P69891, P69892
Accession Number
BC010914
Reactivity
Human
Immunogen
Fusion protein of human HBG1/HBG2
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
0.6 mg/mL
Dilution
WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
16 kDa
Observed Molecular Weight
Refer to figures
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
