COB-187
COB-187 is a potent, selective, and ATP-competitive GSK-3β inhibitor that acts via reversible engagement of Cys-199. This small molecule has demonstrated utility in cellular research, suppressing LPS-induced cytokine and SARS-CoV-2 spike protein-triggered CXCL10 production in vitro.
Product Specifications
CAS Number
1862177-86-3
Field of Research
Signal Transduction, Stem Cell & Developmental Biology
Smiles
S=C1SCC (O) (C=2C=CC=CC2) N1CC=3C=CN=CC3
Molecular Formula
C15H14N2OS2
Molecular Weight
302.41
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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