Philanthotoxin 74 diTFA
Philanthotoxin 74 (PhTx 74) diTFA is a selective AMPA receptor antagonist, potently inhibiting GluR3 and GluR1 subunits with IC50 values of 263 nM and 296 nM, respectively. This tool compound is used in vitro and in vivo to study excitatory synaptic transmission, neurotoxicity, and neurological disease mechanisms.
Product Specifications
CAS Number
401601-12-5
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Smiles
OC (C (F) (F) F) =O.OC (C=C1) =CC=C1C[C@H] (NC (CCC) =O) C (NCCCCCCCNCCCCN) =O.OC (C (F) (F) F) =O
Molecular Formula
C28H44F6N4O7
Molecular Weight
662.66
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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