AF488 Anti-Human CD45 Antibody
This is a AF488 Anti-Human CD45 Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
CD45 is a 180 - 240 kD single chain type I membrane glycoprotein also known as leukocyte common antigen (LCA) and T200. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes or platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and other Src family kinases. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind galectin-1 and to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4.
Synonyms
Receptor-type tyrosine-protein phosphatase C, Ptprc, L-CA, Ly-5, T200, CD45
Gene ID
5788
Swiss Prot
P08575
Reactivity
Human
Clonality
Monoclonal
Conjugation
AF488
Type
Flow Cytometry Antibody
Applications
FC
Assay Type
Antibody
Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Conditions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Host or Source
Mouse
Isotype
Mouse IgG1, κ
Available Sizes
Curated Selection
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