BPR5K230
BPR5K230 is a potent and selective dual inhibitor of MER (IC50=4.1 nM) and AXL (IC50=9.2 nM) receptor tyrosine kinases. It demonstrates robust anti-proliferative activity in vitro and exhibits favorable pharmacokinetics with antitumor efficacy in multiple mouse cancer models, including breast, colon, and liver carcinomas.
Product Specifications
CAS Number
3029897-97-7
Field of Research
Signal Transduction
Smiles
O=C (NC1=CC=C (OC=2N=CN=C3OC (C=4C=NN (C4) C) =C (C5=CC=CC (=C5) CN (C) C) C23) C=C1) C6=CC=CN (C6=O) C7=CC=C (F) C=C7
Molecular Formula
C37H30FN7O4
Molecular Weight
655.68
Storage Conditions
-20°C
Notes
For research use only.
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