Bax Recombinant Antibody, Biotin Conjugated

Product Specifications

Background

Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.

Synonyms

Apoptosis regulator BAX; Bcl-2-like protein 4; Bcl2-L-4; BCL2L4

Gene ID

581

Swiss Prot

Q07812

Cellular Locus

Cytoplasm, Mitochondrion, Membrane bound

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

Bax

Clonality

Recombinant

Isotype

IgG

Conjugation

Biotin

Source

Recombinant human Bak between 20 to 150 amino acids

Applications

WB, IHC-P, IHC-F

Purification

Purified by Protein A.

Concentration

1 mg/ml

Dilution

WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

581

Available Sizes

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