FDW028
FDW028 is a potent and selective inhibitor of fucosyltransferase 8 (FUT8) . It exhibits anti-tumor activity by inducing B7-H3 degradation via defucosylation and chaperone-mediated autophagy pathways, making it a useful tool for studying metastatic colorectal cancer in both cellular and animal models.
Product Specifications
CAS Number
2768426-49-7
Product Name Alternative
Autophagy, FDW 028, FDW028, FUT8
Field of Research
Cell Biology, Immunology & Inflammation, Metabolism Research, Signal Transduction
Purity
98.73% (May vary between batches)
Solubility
DMSO:80 mg/mL (205.94 mM)
Smiles
OC1=CC (=NC2=NC (=NN21) NCC3=CC=C (C=C3) CC) CNCC=4C=CC=CC4
Molecular Formula
C22H24N6O
Molecular Weight
388.47
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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