LE01 Antibody
LE01 is a drug-linker conjugate for antibody-drug conjugates (ADCs), consisting of a cleavable linker and the topoisomerase I inhibitor payload DXd. It is utilized in constructing the HER2-targeting ADC HER2-LE01 for research into targeted cancer therapies, with applications in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
2718125-83-6
Field of Research
Molecular Biology
Smiles
N (C (COC (N (CCNC (CNC ([C@H] (CC1=CC=CC=C1) NC (CNC (CNC (CCCCCN2C (=O) C=CC2=O) =O) =O) =O) =O) =O) C) =O) =O) [C@@H]3C4=C5C (C=6N (C5) C (=O) C7=C (C6) [C@] (CC) (O) C (=O) OC7) =NC=8C4=C (CC3) C (C) =C (F) C8
Molecular Formula
C55H61FN10O14
Molecular Weight
1105.13
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
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