DBM-C5-VC-PAB-MMAE
This drug-linker conjugate, DBM-C5-VC-PAB-MMAE, is designed for ADC synthesis, featuring a maleimide-based linker (DBM) for antibody conjugation and a cleavable valine-citrulline linker attached to the cytotoxic payload MMAE. It is a key reagent for constructing ADCs used in cancer research, enabling the study of targeted drug delivery in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
1644228-55-6
Field of Research
Signal Transduction
Smiles
[C@H] ([C@H] (C (N[C@@H] ([C@@H] (O) C1=CC=CC=C1) C) =O) C) (OC) [C@]2 (N (C (C[C@H] ([C@@H] (N (C ([C@@H] (NC ([C@@H] (N (C (OCC3=CC=C (NC ([C@@H] (NC ([C@@H] (NC (CCCCCN4C (=O) C (Br) =C (Br) C4=O) =O) [C@@H] (C) C) =O) CCCNC (N) =O) =O) C=C3) =O) C) C (C) C) =O) [C@@H] (C) C) =O) C) [C@H] (CC) C) OC) =O) CCC2) [H]
Molecular Formula
C68H103Br2N11O15
Molecular Weight
1474.42
Storage Conditions
-20°C
Notes
For research use only.
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