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Factor XI-IN-2

Factor XI-IN-2 is a Factor XI activation inhibitor with an IC50 of 20 nM. It does not directly inhibit the enzymatic activity of FXIa but specifically binds to the FXI zymogen, allosterically inhibiting the activation process of the FXI zymogen by FXIIa. Factor XI-IN-2 suppresses thrombosis in a rabbit arteriovenous (AV) shunt thrombosis model and can be used in antithrombotic research.

Product Specifications

CAS Number

2563884-39-7

Smiles

O=C (C1=NC=2C=CC (OCC=3C=CC=4SN=NC4C3) =CC2C (=C1) C (=O) N5CCCCC5) N6CCC (N7N=CC=C7) CC6

Molecular Formula

C31H31N7O3S

Molecular Weight

581.7

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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