Cyclooctyne-O-amido-PEG4-PFP ester

This non-cleavable PEG4 linker, featuring a cyclooctyne group and a PFP ester, is designed for constructing antibody-drug conjugates (ADCs) via copper-free click chemistry with azide-functionalized payloads. It is utilized in both in vitro and in vivo research for developing stable, targeted biotherapeutics.