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E3 ligase Ligand 26

E3 Ligase Ligand 26 is a cereblon (CRBN) -binding moiety used to construct PROTAC molecules, such as the SOS1 degrader Compd 10. This ligand enables targeted protein degradation, facilitating the study of SOS1-dependent signaling pathways in cancer research using both cellular and in vivo models.

Product Specifications

CAS Number

2911613-35-7

Field of Research

Molecular Biology, Pharmacology & Drug Discovery

Smiles

O=C (OC=1C (F) =C (F) C (F) =C (F) C1F) C2=CC=C (C (=C2) N3C (=O) NC (=O) CC3) C

Molecular Formula

C18H11F5N2O4

Molecular Weight

414.28

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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