APC Anti-Mouse CD80 Antibody[16-10A1]
Product Specifications
Background
CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.
Abbreviation
CD80
Gene ID
12519
UniProt
Q00609
Host
Armenian Hamster
Reactivity
Mouse
Target
Activation B7-1 antigen; B7; Cd80; T-lymphocyte activation antigen CD80
Clonality
Monoclonal
Clone
16-10A1
Conjugation
APC
Applications
FCM
Field of Research
Cell Biology; Costimulatory Molecules; Immunology; Neuroscience; Neuroscience Cell Markers
Concentration
0.2 mg/mL
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Product Datasheet
https://789.bio/ea/c8evts
Product MSDS
https://789.bio/eb/GubvvD
Citation 01
https://onlinelibrary.wiley.com/doi/abs/10.1002/adhm.202301561
Citation 02
https://pubs.rsc.org/en/content/articlelanding/2024/tb/d4tb01917b
Recommended Usage
6
Isotype
Armenian Hamster IgG
Available Sizes
Curated Selection
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