METTL3-IN-8
METTL3-IN-8 (7460-0250) is a potent and selective METTL3 methyltransferase inhibitor. It has demonstrated efficacy in reducing inflammation in a DSS-induced murine model of colitis, supporting its use as a research tool for studying m6A modification in inflammatory bowel disease (IBD) and related pathways.
Product Specifications
CAS Number
932512-38-4
Field of Research
Signal Transduction
Smiles
O=C1NC=C (NC (=O) NC=2C=CC=C (OC) C2) C (=O) N1
Molecular Formula
C12H12N4O4
Molecular Weight
276.25
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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126716 100 µg
FBXW7 (F-box and WD-40 Domain Protein 7, F-box and WD-40 Domain-containing Protein 7, F-box Protein FBW7, F-box/WD Repeat Protein 7, FBW7, Archipelago Drosophila Homolog of, Archipelago Homolog, AGO, CDC4, DKFZp686F23254, F-box Protein FBX30, FBX30, FBXO30, F-box Protein SEL-10, FBW6, FBXW6, FLJ16457, hAgo, hCdc4, Homolog of C. elegans SEL 10, SEL10, SEL-10)
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