Nrf2-IN-3
Nrf2-IN-3 is a selective inhibitor that targets mutant KEAP1, restoring its ability to repress NRF2 signaling. This compound has been shown to enhance cisplatin sensitivity in mouse xenograft models of mKEAP1 cancer, supporting its use in oncology research for investigating the KEAP1/NRF2 pathway in vitro and in vivo.
Product Specifications
CAS Number
6325-13-9
Product Name Alternative
NRF2
Field of Research
Immunology & Inflammation
Purity
98.07% (May vary between batches)
Solubility
DMSO:100 mg/mL (225.97 mM)
Smiles
O=C (NN=CC=1C=CC=CC1O) CCCSCCCC (=O) NN=CC=2C=CC=CC2O
Molecular Formula
C22H26N4O4S
Molecular Weight
442.53
Storage Conditions
-20°C
Notes
For research use only.
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