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JT001 sodium

JT001 (NLRP3-IN-19) sodium is a specific, orally bioavailable NLRP3 inflammasome inhibitor that blocks its assembly, thereby inhibiting IL-1β release and pyroptosis. It is a research tool for studying NLRP3-driven pathologies, including nonalcoholic steatohepatitis (NASH) and liver fibrosis, in both cellular and animal models.

Product Specifications

CAS Number

2238820-09-0

Field of Research

Immunology & Inflammation

Molecular Formula

C19H22N4NaO4S

Molecular Weight

425.46

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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