DVD-445
DVD-445 is a covalent thioredoxin reductase 1 (TrxR1) inhibitor synthesized via an Ugi reaction, exhibiting potent activity with an IC50 of 0.60 μM. This peptidomimetic compound, featuring an electrophilic warhead, demonstrates anticancer potential in cellular assays and is a useful tool for investigating redox biology in cancer research.
Product Specifications
CAS Number
2375846-41-4
Smiles
C (N (CCOC (/C=C/C (=O) C1=CC=C (F) C=C1) =O) C) (C (NC (C) (C) C) =O) C2=CC=C (F) C=C2
Molecular Formula
C25H28F2N2O4
Molecular Weight
458.5
Storage Conditions
-20°C
Notes
For research use only.
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