PDE1-IN-6
PDE1-IN-6 (6c) is a potent and selective PDE1 inhibitor with an IC50 of 7.5 nM. It demonstrates anti-leukemic activity by suppressing proliferation and promoting apoptosis in acute myelogenous leukemia (AML) cell lines in vitro, supporting its use in oncology and signal transduction research.
Product Specifications
CAS Number
2877017-16-6
Field of Research
Cell Biology, Metabolism Research
Smiles
C (C) (C) (C) N1C2=C (C (=O) N (CC3=CC (F) =CC=C3) C (NCCNC4=CC=C (F) C=C4) =N2) C=N1
Molecular Formula
C24H26F2N6O
Molecular Weight
452.50
Storage Conditions
-20°C
Notes
For research use only.
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