STAM2 (NM_005843) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is closely related to STAM, an adaptor protein involved in the downstream signaling of cytokine receptors, both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM) . Similar to STAM, this protein acts downstream of JAK kinases, and is phosphorylated in response to cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway downstream of JAK kinases upon cytokine stimulation. [provided by RefSeq, Jul 2008]
Synonyms
Hbp; STAM2A; STAM2B
Gene ID
10254
UniProt
O75886
Accession Number mRNA
NM_005843
Chromosomal Location
2q23.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Endocytosis, Jak-STAT signaling pathway
Field of Research
Endocytosis, Jak-STAT signaling pathway
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
58 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
STAM2
Species
Human
Protein ID
NP_005834
Overview
Recombinant protein of human signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 (STAM2)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/10254
Uniprot URL
https://www.uniprot.org/uniprot/O75886
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_005843
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_005834
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
