STAM2 (NM_005843) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is closely related to STAM, an adaptor protein involved in the downstream signaling of cytokine receptors, both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM) . Similar to STAM, this protein acts downstream of JAK kinases, and is phosphorylated in response to cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway downstream of JAK kinases upon cytokine stimulation. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 (STAM2)

Synonyms

Hbp; STAM2A; STAM2B

Gene ID

10254

UniProt

O75886

Accession Number mRNA

NM_005843

Chromosomal Location

2q23.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Endocytosis, Jak-STAT signaling pathway

Field of Research

Endocytosis, Jak-STAT signaling pathway

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

58 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.