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PKM2-IN-6

PKM2-IN-6 (7d) is a potent, orally bioavailable PKM2 inhibitor with an IC50 of 23 nM. It downregulates PKM1/2 mRNA, induces apoptosis and G2/M arrest, and demonstrates antitumor activity in preclinical models, making it a valuable tool for studying triple-negative breast cancer (TNBC) in both cellular and animal studies.

Product Specifications

CAS Number

771467-00-6

Field of Research

Cell Biology, Metabolism Research

Purity

99.83% (May vary between batches)

Solubility

DMSO:100 mg/mL (310.19 mM)

Smiles

N (C1=NC (C=2N3C (=NC2) C=CC=C3) =CS1) C4=C (OC) C=CC=C4

Molecular Formula

C17H14N4OS

Molecular Weight

322.38

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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