Dihydroevocarpine
Dihydroevocarpine induces cytotoxicity in acute myeloid leukemia via suppressing the mTORC1/2 activity[1].
Product Specifications
CAS Number
[15266-35-0]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
MTOR
Type
Natural Products
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dihydroevocarpine.html
Concentration
10mM
Purity
99.62
Solubility
DMSO : 16.67 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1C=C(CCCCCCCCCCCCC)N(C)C2=C1C=CC=C2
Molecular Formula
C23H35NO
Molecular Weight
341.53
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Zhang S, et al. Targeting of mTORC1/2 by dihydroevocarpine induces cytotoxicity in acute myeloid leukemia. J Cell Physiol. 2019;234 (8) :13032-13041.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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