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Dihydroevocarpine

Dihydroevocarpine induces cytotoxicity in acute myeloid leukemia via suppressing the mTORC1/2 activity[1].

Product Specifications

CAS Number

[15266-35-0]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

MTOR

Type

Natural Products

Related Pathways

PI3K/Akt/mTOR

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/dihydroevocarpine.html

Concentration

10mM

Purity

99.62

Solubility

DMSO : 16.67 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C1C=C(CCCCCCCCCCCCC)N(C)C2=C1C=CC=C2

Molecular Formula

C23H35NO

Molecular Weight

341.53

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Zhang S, et al. Targeting of mTORC1/2 by dihydroevocarpine induces cytotoxicity in acute myeloid leukemia. J Cell Physiol. 2019;234 (8) :13032-13041.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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