Venetoclax N-oxide
Venetoclax N-oxide is a metabolite and impurity of Venetoclax (ABT-199), a potent, selective, and orally bioavailable Bcl-2 inhibitor with sub-nanomolar affinity (Ki < 0.01 nM) . This small molecule is widely used in oncology research, particularly for studying apoptosis in hematological cancers, in both cellular and animal models.
Product Specifications
CAS Number
2469279-00-1
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Smiles
CC1 (C) CCC (CN2 (=O) CCN (CC2) c2ccc (C (=O) NS (=O) (=O) c3ccc (NCC4CCOCC4) c (c3) N (=O) =O) c (Oc3cnc4[nH]ccc4c3) c2) =C (C1) c1ccc (Cl) cc1
Molecular Formula
C45H50ClN7O8S
Molecular Weight
884.44
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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