AUTAC1

AUTAC1 is a MetAP2-targeted AUTAC degrader that induces the autophagic clearance of MetAP2 and FKBP12. This small molecule probe is useful for studying targeted protein degradation, autophagy pathways, and PROTAC development in both cellular and animal models of cancer research.

Product Specifications

CAS Number

2241669-09-8

Product Name Alternative

AUTACs

Field of Research

Cell Biology, Pharmacology & Drug Discovery

Purity

99.45% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (3.54 mM) ; DMSO:80 mg/mL (85.92 mM)

Smiles

C[C@@]1 ([C@@]2 ([C@@]3 (CO3) CC[C@@H] (OC (NCCCOCCOCCOCCCNC ([C@H] (CSC=4N (CC5=CC=C (F) C=C5) C6=C (N4) C (=O) N=C (N) N6) NC (C) =O) =O) =O) [C@H]2OC) [H]) [C@H] (CC=C (C) C) O1