ROS-ERS inducer 1

ROS-ERS inducer 1 is a platinum-based N-heterocyclic carbene complex that triggers immunogenic cell death (ICD) via endoplasmic reticulum stress and reactive oxygen species. This mechanism promotes the emission of damage-associated molecular patterns (DAMPs), demonstrating potent anticancer activity in hepatocellular carcinoma (HCC) models, both in vitro and in vivo, surpassing the efficacy of cisplatin.