Recombinant Human IL-5 Protein (Fc Tag)

Interleukin 5 (IL-5) is a member of the interleukin family with a length of 115 amino acids. Interleukins are a group of cytokines (secreted proteins/signaling molecules) that were first seen to be expressed by white blood cells (leukocytes) and has been found in a wide variety of body cells. Interleukin 5 or IL-5 is produced by T helper-2 cells and mast cells. It helps to stimulate B cell growth and increase immunoglobulin secretion and is considered a key mediator in eosinophil activation. Interleukin 5 (IL-5) has long been associated with several allergic diseases , including allergic rhinitis and asthma. Growth in the number of circulating , airway tissue , and induced sputum eosinophils have been observed in patients with these diseases. IL-5 also had something with the terminally differentiated granulocyte eosinophils. IL-5 was originally found as an eosinophil colony-stimulating factor. It has been proved to be a major regulator of eosinophil accumulation in tissues and can modulate eosinophil behavior at every stage from maturation to survival.

Nterleukin; Interleukin; IL5; EDF; IL-5; TRF; BCDFII; B-cell differentiation factor I; B-cell growth factor I; BCGF-II; Cytotoxic T-lymphocyte inducer; E-CSF; Eosinophil differentiation factor; ESGF; Interleukin-5; nterleukin-5; T-cell replacing factor

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.