β-Glucuronide-dPBD-PEG5-NH2
β-Glucuronide-dPBD-PEG5-NH2 is a cleavable proagent for synthesizing antibody-drug conjugates (ADCs) . Its β-glucuronide linker enables targeted drug release, reducing systemic toxicity. This compound demonstrates antitumor activity in research settings by inducing apoptosis and cell cycle arrest, applicable in both in vitro and in vivo cancer studies.
Product Specifications
CAS Number
2246363-68-6
Field of Research
Cell Biology, Stem Cell & Developmental Biology
Smiles
[H][C@@]12CC (=C) CN1C (=O) c1cc (OC) c (OCCCCCOc3cc4N (C (O) [C@]5 ([H]) CC (=C) CN5C (=O) c4cc3OC) C (=O) OCc3ccc (O[C@@H]4O[C@@H] ([C@@H] (O) [C@H] (O) [C@H]4O) C (O) =O) c (c3) C (=O) NCCOCCOCCOCCOCCOCCON) cc1N (C2O) C (=O) OCc1ccc (O[C@@H]2O[C@@H] ([C@@H] (O) [C@H] (O) [C@H]2O) C (O) =O) c (c1) C (=O) NCCOC
Molecular Formula
C78H101N7O35
Molecular Weight
1696.66
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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