(S, R, S) -AHPC-O-Ph-PEG1-NH2
(S, R, S) -AHPC-O-Ph-PEG1-NH2 (VH032-O-Ph-PEG1-NH2) is a VHL-based E3 ligase ligand-linker conjugate used to construct PROTAC molecules. It serves as a key component in PROTAC EED degrader-1, a potent degrader (pKD 9.02) of the EED protein for targeted protein degradation research in biochemical and cellular studies.
Product Specifications
CAS Number
2361117-24-8
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Smiles
Cc1ncsc1-c1ccc (CNC (=O) [C@@H]2C[C@@H] (O) CN2C (=O) [C@@H] (NC (=O) COc2ccc (OCCN) cc2) C (C) (C) C) cc1
Molecular Formula
C32H41N5O6S
Molecular Weight
623.76
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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