Isoformononetin-d3

Isoformononetin-d3 is the deuterium labeled Isoformononetin (HY-N7501) . Isoformononetin is an analog of Daidzein (HY-N0019) and has immunoprotective effects. Isoformononetin inhibits the differentiation of Th17 and B-cells lymphopoesis to promote osteogenesis in estrogen-deficient bone loss conditions[1][2].

Product Specifications

UNSPSC

12352005

Target

Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Purity

98.64

Solubility

DMSO : 250mg/mL (ultrasonic)

Smiles

O=C1C2=CC=C(OC([2H])([2H])[2H])C=C2OC=C1C3=CC=C(O)C=C3

Molecular Formula

C16H9D3O4

Molecular Weight

271.28

References & Citations

[1]Mansoori MN, et al. Methoxyisoflavones formononetin and isoformononetin inhibit the differentiation of Th17 cells and B-cell lymphopoesis to promote osteogenesis in estrogen-deficient bone loss conditions. Menopause. 2016 May;23 (5) :565-76.|[2]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.