LL-K9-3
LL-K9-3 is a selective hydrophobic tag (HyT) -based degrader that induces the synchronous degradation of the CDK9-cyclin T1 complex. This mechanism effectively reduces AR and cMyc expression in cellular models like 22RV1 cells, providing a tool for oncology research targeting transcriptional dependencies in cancers.
Product Specifications
CAS Number
2809353-52-2
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Smiles
O=S (CCNC (CO[C@H]1[C@@H] (CC[C@H] (C1) C) C (C) C) =O) (N2CCC (CC2) C (NC3=NC=C (SCC4=NC=C (C (C) (C) C) O4) S3) =O) =O
Molecular Formula
C31H49N5O6S3
Molecular Weight
683.94
Storage Conditions
-20°C
Notes
For research use only.
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