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J-1048

J-1048 is a selective ALK5 inhibitor that blocks the TGF-β/Smad pathway. It has been shown to effectively reduce liver fibrosis in a TAA-induced mouse model, making it a valuable tool for studying fibrotic diseases in both in vivo and in vitro research settings.

Product Specifications

CAS Number

2374772-60-6

Field of Research

Cardiovascular Research, Signal Transduction

Smiles

C (C (NC1=CC (F) =CC=C1) =S) N2C=C (C (=N2) C=3N=C (C) C=CC3) C4=CC=5C (C=C4) =NSN5

Molecular Formula

C23H17FN6S2

Molecular Weight

460.55

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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