J-1048
J-1048 is a selective ALK5 inhibitor that blocks the TGF-β/Smad pathway. It has been shown to effectively reduce liver fibrosis in a TAA-induced mouse model, making it a valuable tool for studying fibrotic diseases in both in vivo and in vitro research settings.
Product Specifications
CAS Number
2374772-60-6
Field of Research
Cardiovascular Research, Signal Transduction
Smiles
C (C (NC1=CC (F) =CC=C1) =S) N2C=C (C (=N2) C=3N=C (C) C=CC3) C4=CC=5C (C=C4) =NSN5
Molecular Formula
C23H17FN6S2
Molecular Weight
460.55
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog