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PPARα agonist 3

PPARα agonist 3 (Compound A229) is a PPARα agonist (EC50: 590 nM). PPARα agonist 3 inhibits TBHP or 4-HNE -induced production of ROS[1].

Product Specifications

UNSPSC

12352005

Target

PPAR; Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Vitamin D Related/Nuclear Receptor

Applications

COVID-19-anti-virus

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/pparα-agonist-3.html

Smiles

O=C(O)C1=CC(NCC2=CC=C(C3=CC=C(F)C=C3)C=C2)=CC(F)=C1

Molecular Formula

C20H15F2NO2

Molecular Weight

339.34

References & Citations

[1]Bo Hu, et al. Design and Assessment of First-Generation Heterobifunctional PPARα/STING Modulators. ACS Medicinal Chemistry Letters Article ASAP

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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