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Fmoc-Lys-OH hydrochloride

Fmoc-Lys-OH hydrochloride is a alkyl-chain-based PROTAC linker. Fmoc-Lys-OH hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . (In Vitro) :PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

Product Specifications

CAS Number

139262-23-0

Purity

>98% (HPLC)

Solubility

In Vitro: DMSO : 125 mg/mL (308.73 mM)

Smiles

Cl.NCCCC[C@H] (NC (=O) OCC1c2ccccc2-c2ccccc12) C (O) =O

Molecular Formula

C21H25ClN2O4

Molecular Weight

404.89

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

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