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Protein deglycase DJ-1 against-1

This small molecule inhibitor (compound 23) is a blood-brain barrier permeable deglycase DJ-1-targeting compound. It binds to the C106 residue to prevent protein over-oxidation, protecting against oxidative stress. It has shown efficacy in restoring neuronal function and motor deficits in MPTP-induced in vivo models of Parkinson's disease.

Product Specifications

CAS Number

724737-74-0

Field of Research

Cell Biology, Neuroscience, Pharmacology & Drug Discovery

Purity

97.23% (May vary between batches)

Solubility

DMSO:16 mg/mL (38.33 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.79 mM)

Smiles

O=C (NC=1C=CC (=CC1) C=2N=C3C (=CC=CN3C2) C) C4=CC (OC) =C (OC) C (OC) =C4

Molecular Formula

C24H23N3O4

Molecular Weight

417.46

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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