Eleven-Nineteen-Leukemia Protein IN-1
The small molecule inhibitor Eleven-Nineteen-Leukemia Protein IN-1 potently targets the ENL YEATS domain with an IC50 of 14.5 nM. Its binding stabilizes the ENL protein in vitro, making it a valuable chemical probe for studying transcriptional regulation in acute leukemia and related epigenetic research fields.
Product Specifications
CAS Number
2894121-68-5
Field of Research
Cancer Biology, Epigenetics & Chromatin
Smiles
C[C@H]1CCCN1CC1=NC2=CC (NC (=O) C3=CC4=C (C=C3) N (CCN3CCOCC3) N=C4) =CC=C2N1
Molecular Formula
C27H33N7O2
Molecular Weight
487.6
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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