MDM2-p53-IN-16
MDM2-p53-IN-16 is a highly potent small molecule inhibitor of the MDM2-p53 interaction with an IC50 of 4.3 nM. It reactivates p53 function, inducing apoptosis and cell-cycle arrest in Glioblastoma Multiforme (GBM) cells in vitro, making it a valuable chemical probe for oncology research and p53 pathway studies.
Product Specifications
CAS Number
1917350-09-4
Field of Research
Cancer Biology; Cell Biology, Cell Biology
Smiles
C (C (N[C@@H] (CC1=CC=CC=C1) C (N[C@H] (C (OC) =O) CC (C) C) =O) =O) (=O) C2=C (NC=3C2=CC=CC3) C4=CC=CC=C4
Molecular Formula
C32H33N3O5
Molecular Weight
539.62
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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