TrkA-IN-3
TrkA-IN-3 is a highly potent and subselective allosteric inhibitor of TrkA (IC50 = 22.4 nM) with >8000-fold selectivity over TrkB/C. Its profile makes it a valuable chemical probe for investigating TrkA-specific signaling in pain pathways, suitable for both in vitro biochemical assays and in vivo pain research models.
Product Specifications
CAS Number
3026111-73-6
Field of Research
Signal Transduction
Purity
98.37% (May vary between batches)
Smiles
O=C (O) C1=CN=C (C=2C=CC=CC2) C (=C1) NC (=O) C=3C=CC (=C (C3) C4=NN (C=C4) C) C (F) (F) F
Molecular Formula
C24H17F3N4O3
Molecular Weight
466.41
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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