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Boc-N-amido-PEG3-acid

Boc-N-amido-PEG3-acid is a polyethylene glycol (PEG) spacer used in constructing PROTAC molecules. It connects a target-binding ligand to an E3 ligase recruiter, facilitating intracellular protein degradation via the ubiquitin-proteasome system. This linker is widely applied in both in vitro biochemical assays and in vivo proof-of-concept studies for targeted protein degradation research.

Product Specifications

CAS Number

1347750-75-7

Field of Research

Cell Biology, Pharmacology & Drug Discovery

Smiles

O (C (NCCOCCOCCOCCC (O) =O) =O) C (C) (C) C

Molecular Formula

C14H27NO7

Molecular Weight

321.37

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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