MC-VA-PAB-Exatecan
MC-VA-PAB-Exatecan is a cleavable drug-linker conjugate for constructing antibody-drug conjugates (ADCs) . It incorporates the potent topoisomerase I inhibitor Exatecan, enabling targeted delivery and release of the cytotoxic payload. This conjugate is a key research tool for developing novel ADC therapeutics, with applications in both in vitro cytotoxicity assays and in vivo antitumor efficacy studies.
Product Specifications
CAS Number
2680543-57-9
Product Name Alternative
DrugLinker Conjugates for ADC, DrugLinkerConjugatesforADC
Field of Research
Molecular Biology, Pharmacology & Drug Discovery
Solubility
DMF:≥ 80 mg/mL; DMSO:80 mg/mL (84.39 mM)
Smiles
N (C (OCC1=CC=C (NC ([C@@H] (NC ([C@@H] (NC (CCCCCN2C (=O) C=CC2=O) =O) [C@@H] (C) C) =O) C) =O) C=C1) =O) [C@@H]3C4=C5C (C=6N (C5) C (=O) C7=C (C6) [C@] (CC) (O) C (=O) OC7) =NC=8C4=C (CC3) C (C) =C (F) C8
Molecular Formula
C50H54FN7O11
Molecular Weight
948.02
Storage Conditions
-20°C
Notes
For research use only.
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