Oscillamide C

Oscillamide C (Compound 2), a ureido-containing cyclic peptide, is a Protein phosphatase 1 (PP1) and Protein phosphatase 2A (PP2A) inhibitor with IC50s of 0.90 and 1.33 μM for PP1 and PP2A, respectively. Oscillamide C can be isolated from the cyanobacteria Planktothrix agardhii and P. rubescens. Oscillamide C can be used for cancers research[1].

Product Specifications

CAS Number

[365400-08-4]

UNSPSC

12352209

Target

Phosphatase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer

Smiles

OC(C=C1)=CC=C1CC[C@@H]2N(C([C@@H](NC([C@](NC([C@@H](CCCCNC([C@@H](NC2=O)CC3=CC=CC=C3)=O)NC(N[C@H](C(O)=O)CCCNC(N)=N)=O)=O)([H])[C@@H](C)CC)=O)CCC4=CC=C(C=C4)O)=O)C

Molecular Formula

C49H68N10O10

Molecular Weight

957.13

References & Citations

[1]Sano T, et al. Isolation of new protein phosphatase inhibitors from two cyanobacteria species, Planktothrix spp. J Nat Prod. 2001 Aug;64 (8) :1052-5.