Hemopressin (human, mouse)
Product Specifications
UNSPSC Description
Hemopressin is a nonapeptide derived from the α1-chain of hemoglobin, is originally isolated from rat brain homogenates. Hemopressin is orally active, selective and inverse agonist of CB1 cannabinoid receptors. Hemopressin exerts antinociceptive action in inflammatory pain models[1][2].
Target Antigen
Cannabinoid Receptor
Type
Peptides
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/hemopressin-human-mouse.html
Purity
99.95
Solubility
H2O : ≥ 16.67 mg/mL
Smiles
O=C(O)[C@H](CC1=CNC=N1)NC([C@H](CO)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](CCCCN)NC([C@H](CC2=CC=CC=C2)NC([C@H](CC(N)=O)NC([C@H](C(C)C)NC([C@H]3NCCC3)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Weight
1054.24
References & Citations
[1]Garron T Dodd, et al. The peptide hemopressin acts through CB1 cannabinoid receptors to reduce food intake in rats and mice. J Neurosci. 2010 May 26;30(21):7369-76.|[2]Elaine F Toniolo, et al. Hemopressin, an inverse agonist of cannabinoid receptors, inhibits neuropathic pain in rats. Peptides. 2014 Jun;56:125-31.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P1091/Hemopressin-human-mouse-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P1091/Hemopressin-human-mouse-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1314035-51-2
Available Sizes
Curated Selection
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