M-PEG-azide (MW 20000)
M-PEG-azide (MW 20000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. m-PEG-azide (MW 20000) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Product Specifications
UNSPSC
12352211
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/m-peg-azide-mw-20000.html
Solubility
10 mM in DMSO
Smiles
COCCOCCN=[N+]=[N-].[n].[MW20000]
Molecular Weight
20000 (Average)
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6469609-02 5x 0.1 mL
Cofilin, Phosphorylated (Ser3) (MaxLight 750)
Sign In for Pricing
View Details 
MBS6469187-01 0.2 mL
CLASP2, CT (CLIP-associating Protein 2, Cytoplasmic Linker-associated Protein 2, Protein Orbit Homolog 2, hOrbit2, KIAA0627) (APC)
Sign In for Pricing
View Details MBS6469187-02 5x 0.2 mL
CLASP2, CT (CLIP-associating Protein 2, Cytoplasmic Linker-associated Protein 2, Protein Orbit Homolog 2, hOrbit2, KIAA0627) (APC)
Sign In for Pricing
View Details WTB81560-01 50 mg
4- (8-Chloro-2,3-dihydro-1,4-benzodioxin-6-yl) -1H-pyrrole-3-carboxylic acid
Sign In for Pricing
View Details